High-Level folate production in fermented foods by the B12 producer Lactobacillus reuteri JCM1112.

نویسندگان

  • Filipe Santos
  • Arno Wegkamp
  • Willem M de Vos
  • Eddy J Smid
  • Jeroen Hugenholtz
چکیده

We observed that Lactobacillus reuteri JCM1112 produces B(12) and folate. However, the folate/B(12) mass ratio found was far below that desired for human consumption ( approximately 170:1). We used metabolic engineering applying genetic and physiological approaches to improve this ratio and developed a generic and natural process that significantly increases folate production.

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عنوان ژورنال:
  • Applied and environmental microbiology

دوره 74 10  شماره 

صفحات  -

تاریخ انتشار 2008